Modern aspects of diagnosis and treatment of kidney cancer
Summary. In recent decades, there has been an increase in the frequency of kidney cancer detection in many countries of the world, which may be due to the improvement of methods of diagnosing the disease and the growing attention of scientists to this type of cancer. During the satellite symposium «Send cancer to the knockout» of the International scientific and practical conference «UUOS–2024. Achievements and prospects in the treatment of tumors and diseases of the genitourinary system» the first report was presented by the leading researcher of the National Cancer Institute, doctor of medical sciences Oleksandr Eduardovych Stakhovsky, who had told about the new classification of the World Health Organization, 2022 of kidney cancer, which can be the basis for improving the prognosis of the kidney cancer and the development of more personalized and molecularly based methods of the disease’s treatment in the future. Professor of the Department of urology, nephrology, and andrology of the Kharkiv national medical university, head of the department of urology of the Shapoval Regional Medical Clinical Center of Urology and Nephrology, doctor of medical sciences Dmytro Volodymyrovych Shchukin highlighted the treatment of stage II–III kidney cancer depending on the likelihood of recurrence. The speaker focused special attention on the results of the KEYNOTE-564 study involving patients with renal cell cancer and an increased risk of recurrence after surgery, which had shown a significant advantage of the PD-1 inhibitor (pembrolizumab) use in the adjuvant therapy in disease-free survival and overall survival, which is a huge breakthrough in the treatment of patients with renal cell cancer. Thus, during the satellite symposium «Send cancer to the knockout» of the International scientific and practical conference «UUOS–2024. Achievements and prospects in the treatment of tumors and diseases of the genitourinary system» the importance of the histological structure of a kidney tumor for the prognosis of the course of the disease, as well as the modern possibilities of adjuvant therapy in renal cell cancer patients, were shown.
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