Radiation diagnosis for assessment of local tumor distribution in patients with cervical cancer
Головко Т.С.1, Яроцький М.Є.2, Бакай О.А.1, Yarotska I.V.3, Лигирда Н.Ф.1
- 1National Cancer Institute, Kyiv
- 2Limited liability company Academic Medical Centre, Kyiv
- 3Shupik National Medical Academy of Postgraduate Education, Kyiv
Summary. With verified cervical cancer, the main task of radiation studies is tumor process spread evaluation since this has a profound effect on the treatment tactics choice and prognosis. Aim of study was Magnetic Resonance study optimizing for tumor process local spread evaluation in patients with CC via comparing the usefulness of different Magnetic Resonance Imaging sequences. Material and methods: 62 patients with Cervical cancer were examined by Magnetic Resonance Imaging on tomograph 1,5 Т using contrast enhancement and Diffusion-weighted imaging (DWI). Pre-operation radiation diagnostics results of tumor spread were compared with surgical and pathologic data. Results. The diagnostic efficiency of different methods of radiation testing for the evaluation of local tumor distribution in patients with Cervical cancer was determined. Using contrast didn`t increase informative Magnetic Resonance Imaging in evaluation of local tumor distribution. False overstatement degree distribution tumor process was due to intensive accumulation contrast substance around the tumor in consequence of reaction inflammation. Use of DWI allowed to reduce the number of false positive results, which significantly increased the efficiency of Magnetic Resonance Imaging (p<0.05): the positive predictive value, sensitivity, specificity and accuracy were 83,3; 90,9; 96,0 and 95,1% respectively. Conclusions. The most informative combination for assessing the local spread of the tumor process in patients with verified cervical cancer is the combination of the native sequence with DWI, so it is advisable to include DWI in the Magnetic Resonance protocol of these patients.
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