Erlotinib efficacy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer

Summary. In a prospective, randomized, controlled phase III study EURTAC was shown, that the use of the erlotinib in the first-line treatment of patients of the European population with advanced non-small cell lung cancer (NSCLC), and tumors that have mutations that activate EGFR, almost double the rate of progression-free survival. These data are similar to the results of the phase III study OPTIMAL, which included patients with the same form of NSCLC, related to the Asian population.