Cryosurgery with local microwave hyperthermia in oral cavity cancer treatment

Summary. Complex treatment method employing chemo-radiation therapy (CRT), tumor cryodestruction (CD) followed by local microwave hyperthermia in 24 hours was developed and applied at cancer of mucous membrane of oral cavity and tongue. Treatment results comparative analysis was made for two groups of patients. Control group included 38 patients with cancer of mucous membrane of oral cavity and tongue, whose complex treatment included chemo-radiation therapy (CRT) and tumor cryodestruction (CD). In experimental group of 20 analogous patients, local microwave hyperthermia in 24 hours following CD was added to CRT and CD. Cancer relapse rate in first 12 months of follow-up was – in control group 31.6±7.54%, in experimental group 7.70±5.96%. Regional metastases rate for all observation period was 34.2±7.96% in control group and 0% in experimental group.