Ovarian endometrioid carcinoma, cytomorphological, cytogenetical and immunocytochemical findings

Summary. Cytomorphological, cytogenetical and immunocytochemical findings in ovarian endometrioid carcinoma are presented on the basis of scrapings from tumors removed during surgery in 4 women of different ages. Two cytogram variants of round-oval and prismatic cells were identified. High counts in both total nucleoli and their active forms (compact and transitional nucleolonemal) were detected, which may be indicative of a poor prognosis of the disease. Immunocytochemical study with mAb (cytokeratin 7, 20) and epithelial antigen (Ber-EP4) can be helpful in the differential diagnosis of ovarian cancer morphological variants.