Risk factors of pancreatic fistula in different types of pancreatectomies

Summary. The results of treatment of 101 patients with pancreatic cancer in Kyiv Center for Liver, Pancreas and Bile Ducts Surgery du­ring 2010–2014 years are represented. 82 patients underwent proximal and 19 patients — distal resection of the pancreas, among them were multivisceral resections and cryoablation of the residual tumor. Postoperative pancreatic fistula (POPF) was defined according to the International Study Group of Pancreatic Surgery. Such factors as mild morphological structure of pancreas, intraoperative blood loss >1000 ml, body mass index >25 kg/m², albumin blood level <35 g/l before operation and multivisceral resection and/or cryoablation of the residual tumor were significantly associated with the occurrence of pancreatic fistula (p<0.01; χ²-test). Preoperative assessment of extent of the procedure may help in prediction of POPF formation. Preoperative correction of hypoalbuminemia and decrease of intraoperative blood loss by improving the surgical skills and use of modern electrosurgical generators may help prevent POPF formation.